@prefix this: <http://www.tkuhn.ch/bel2nanopub/RAOZBiGKySGZjGuh2JGNB0eofWe-Uyx1Q1tDqH-WZyI5k> .
@prefix sub: <http://www.tkuhn.ch/bel2nanopub/RAOZBiGKySGZjGuh2JGNB0eofWe-Uyx1Q1tDqH-WZyI5k#> .
@prefix beldoc: <http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix dce: <http://purl.org/dc/elements/1.1/> .
@prefix pav: <http://purl.org/pav/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix belv: <http://www.selventa.com/vocabulary/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix Protein: <http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080> .
@prefix mgi: <http://www.informatics.jax.org/marker/MGI:> .
@prefix geneProductOf: <http://purl.obolibrary.org/obo/RO_0002204> .
@prefix chebi: <http://www.ebi.ac.uk/chebi/searchId.do?chebiId=> .
@prefix obo: <http://purl.obolibrary.org/obo/> .
@prefix occursIn: <http://purl.obolibrary.org/obo/BFO_0000066> .
@prefix species: <http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=> .
@prefix pubmed: <http://www.ncbi.nlm.nih.gov/pubmed/> .
@prefix orcid: <http://orcid.org/> .
sub:Head {
  this: np:hasAssertion sub:assertion ;
    np:hasProvenance sub:provenance ;
    np:hasPublicationInfo sub:pubinfo ;
    a np:Nanopublication .
}
sub:assertion {
  sub:_1 geneProductOf: mgi:1197012 ;
    a Protein: .
  sub:_2 geneProductOf: mgi:97747 ;
    a Protein: .
  sub:_3 rdf:object sub:_2 ;
    rdf:predicate belv:decreases ;
    rdf:subject chebi:6494 ;
    a rdf:Statement .
  sub:_4 occursIn: obo:CL_0000235 , species:10090 ;
    rdf:object sub:_3 ;
    rdf:predicate belv:increases ;
    rdf:subject sub:_1 ;
    a rdf:Statement .
  sub:assertion rdfs:label "a(CHEBI:lipopolysaccharide) -| p(MGI:Pparg)" , "p(MGI:Aebp1) -> (a(CHEBI:lipopolysaccharide) -| p(MGI:Pparg))" .
}
sub:provenance {
  beldoc: dce:description "Approximately 61,000 statements." ;
    dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ;
    dce:title "BEL Framework Large Corpus Document" ;
    pav:authoredBy sub:_6 ;
    pav:version "20131211" .
  sub:_5 prov:value "To test this hypothesis, whole cell protein extracts isolated fromvehicle- and LPS-treated AEBP1+/+ and AEBP1?/? macrophages were subjected to SDS-PAGE followed by immunoblotting (Fig. 3A). Histograms illustrating relative protein levels of PPAR1 and LXR normalized based on actin expression are shown in Fig. 3B. As shown in Fig. 3A and B, although LPS significantly inhibits PPAR1 and LXR expression in AEBP1+/+ macrophages, AEBP1 ablation almost completely interferes with LPS-induced suppression of PPAR1 and LXR expression (80% versus 20% reduction, respectively, 48 h post LPS treatment)." ;
    prov:wasQuotedFrom pubmed:19166963 .
  sub:_6 rdfs:label "Selventa" .
  sub:assertion prov:hadPrimarySource pubmed:19166963 ;
    prov:wasDerivedFrom beldoc: , sub:_5 .
}
sub:pubinfo {
  this: dct:created "2014-07-03T14:33:32.193+02:00"^^xsd:dateTime ;
    pav:createdBy orcid:0000-0001-6818-334X , orcid:0000-0002-1267-0234 .
}