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All rights reserved. http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAOQLZZqaDhl7zyj7zv___ixt6Rmdawe8zqFZfBtiPnsw#_4 http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/version 20131211 http://www.tkuhn.ch/bel2nanopub/RAOQLZZqaDhl7zyj7zv___ixt6Rmdawe8zqFZfBtiPnsw#_3 http://www.w3.org/ns/prov#value Differentiation of skin stem cells into hair follicles (HFs) requires the inhibition of beta-catenin degradation, which is controlled by a complex containing axin and the protein kinase GSK3beta. Using conditional gene targeting in mice, we show now that the small GTPase Cdc42 is crucial for differentiation of skin progenitor cells into HF lineage and that it regulates the turnover of beta-catenin. http://www.tkuhn.ch/bel2nanopub/RAOQLZZqaDhl7zyj7zv___ixt6Rmdawe8zqFZfBtiPnsw#_3 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/16510873 http://www.tkuhn.ch/bel2nanopub/RAOQLZZqaDhl7zyj7zv___ixt6Rmdawe8zqFZfBtiPnsw#_4 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RAOQLZZqaDhl7zyj7zv___ixt6Rmdawe8zqFZfBtiPnsw#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/16510873 http://www.tkuhn.ch/bel2nanopub/RAOQLZZqaDhl7zyj7zv___ixt6Rmdawe8zqFZfBtiPnsw#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RAOQLZZqaDhl7zyj7zv___ixt6Rmdawe8zqFZfBtiPnsw#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RAOQLZZqaDhl7zyj7zv___ixt6Rmdawe8zqFZfBtiPnsw#_3 http://www.tkuhn.ch/bel2nanopub/RAOQLZZqaDhl7zyj7zv___ixt6Rmdawe8zqFZfBtiPnsw#pubinfo http://www.tkuhn.ch/bel2nanopub/RAOQLZZqaDhl7zyj7zv___ixt6Rmdawe8zqFZfBtiPnsw http://purl.org/dc/terms/created 2014-07-03T14:32:56.866+02:00 http://www.tkuhn.ch/bel2nanopub/RAOQLZZqaDhl7zyj7zv___ixt6Rmdawe8zqFZfBtiPnsw http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RAOQLZZqaDhl7zyj7zv___ixt6Rmdawe8zqFZfBtiPnsw http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234