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All rights reserved. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAOAbFgIPjDa5WmXpsD0GzILnxL72sgtC_9nyq6foUtiw#_4 http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/version 1.4 http://www.tkuhn.ch/bel2nanopub/RAOAbFgIPjDa5WmXpsD0GzILnxL72sgtC_9nyq6foUtiw#_3 http://www.w3.org/ns/prov#value Our data show that addition of HGF suppressed AIF expression and increased cisplatin resistance. knockout of FAK gene increased AIF expression and drug sensitivity. Re-introduction of FAK gene, on the other hand, restored drug resistance. These results suggested that HGF might induce cisplatin resistance via c-Met to activate FAK and down-regulate AIF expression. http://www.tkuhn.ch/bel2nanopub/RAOAbFgIPjDa5WmXpsD0GzILnxL72sgtC_9nyq6foUtiw#_3 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/18096875 http://www.tkuhn.ch/bel2nanopub/RAOAbFgIPjDa5WmXpsD0GzILnxL72sgtC_9nyq6foUtiw#_4 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RAOAbFgIPjDa5WmXpsD0GzILnxL72sgtC_9nyq6foUtiw#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/18096875 http://www.tkuhn.ch/bel2nanopub/RAOAbFgIPjDa5WmXpsD0GzILnxL72sgtC_9nyq6foUtiw#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RAOAbFgIPjDa5WmXpsD0GzILnxL72sgtC_9nyq6foUtiw#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RAOAbFgIPjDa5WmXpsD0GzILnxL72sgtC_9nyq6foUtiw#_3 http://www.tkuhn.ch/bel2nanopub/RAOAbFgIPjDa5WmXpsD0GzILnxL72sgtC_9nyq6foUtiw#pubinfo http://www.tkuhn.ch/bel2nanopub/RAOAbFgIPjDa5WmXpsD0GzILnxL72sgtC_9nyq6foUtiw http://purl.org/dc/terms/created 2014-07-03T14:30:52.421+02:00 http://www.tkuhn.ch/bel2nanopub/RAOAbFgIPjDa5WmXpsD0GzILnxL72sgtC_9nyq6foUtiw http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RAOAbFgIPjDa5WmXpsD0GzILnxL72sgtC_9nyq6foUtiw http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234