@prefix this: <http://purl.org/np/RAOAL0YYmV-PmU9PMNGCc1sVdoF-nZ5XOwP6lt1psqNKM> .
@prefix sub: <http://purl.org/np/RAOAL0YYmV-PmU9PMNGCc1sVdoF-nZ5XOwP6lt1psqNKM#> .
@prefix drugbank: <http://identifiers.org/drugbank/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix mondo: <http://purl.obolibrary.org/obo/MONDO_> .
@prefix pav: <http://purl.org/pav/> .
@prefix infores: <https://w3id.org/biolink/infores/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix ntemplate: <https://w3id.org/np/o/ntemplate/> .
@prefix orcid: <https://orcid.org/> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix pmid: <http://www.ncbi.nlm.nih.gov/pubmed/> .
@prefix ncit: <http://purl.obolibrary.org/obo/NCIT_> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix biolink: <https://w3id.org/biolink/vocab/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix npx: <http://purl.org/nanopub/x/> .
sub:Head {
   this: np:hasAssertion sub:assertion ;
    np:hasProvenance sub:provenance ;
    np:hasPublicationInfo sub:pubInfo ;
    a np:Nanopublication .
}
sub:assertion {
   drugbank:DB01175 a biolink:Drug ;
    rdfs:label "Escitalopram" ;
    biolink:category biolink:Drug .
  mondo:0001780 a biolink:Disease ;
    rdfs:label "Premature ejaculation (disease)" ;
    biolink:category biolink:Disease .
  sub:association rdf:object mondo:0001780 ;
    rdf:predicate biolink:treats ;
    rdf:subject drugbank:DB01175 ;
    a biolink:ChemicalToDiseaseOrPhenotypicFeatureAssociation ;
    rdfs:label "SSRIs including paroxetine, fluoxetine and escitalopram have been found as effective treatment for patients with premature ejaculation (Arafa and Shamloul, 2007). Premature ejaculation is also treated with clomipramine and sertraline (Balon, 1996; McMahon, 1998), as well as with dapoxetine, a member of the SSRI family, which is however not used to treat depression (Andersson et al., 2006)" ;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory ;
    biolink:category biolink:ChemicalToDiseaseOrPhenotypicFeatureAssociation ;
    biolink:has_population_context sub:context ;
    biolink:publications pmid:31622593 ;
    biolink:relation ncit:C94303 .
  sub:context a biolink:Cohort ;
    rdfs:label "Adults" ;
    biolink:category biolink:Cohort .
}
sub:provenance {
   sub:assertion prov:wasAttributedTo orcid:0000-0002-7641-6446 .
}
sub:pubInfo {
   sub:sig npx:hasAlgorithm "RSA" ;
    npx:hasPublicKey "MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCR9fz0fKCdWOWC+pxhkQhEM/ppbdIYe5TLSdj+lJzSlv9mYBaPgrzVezSwwbmhlHBPDZa4/vHycU315BdmUGq+pXllp9+rWFfrb+kBJwhZjpG6BeyyXBsRFz4jmQVxl/ZYHilQTh/XalYzKkEAyTiEMPee4Kz61PaWOKH24CsnOQIDAQAB" ;
    npx:hasSignature "hNJsBh2DW1hqNzgyNJuhAUunhTJnmc48L2tdy2AL2J9EE/n3v5uBrtG1NSFehuxkkJXCOrsZYtbvWvQssC8aqhV0DvXzqIpeDSNBWb/OICZQbLTwy0pfy1hlJxI9yQFsmFDYS5Fy3HyRblb0ocQgGhbEgZ997QWrUcI+2mPgM4c=" ;
    npx:hasSignatureTarget this: .
  this: prov:generatedAtTime "2022-09-16T11:48:41.724521"^^xsd:dateTime ;
    prov:wasAttributedTo orcid:0000-0002-1501-1082 ;
    ntemplate:wasCreatedFromTemplate <http://purl.org/np/RAhNHZw6Urw_Mccs4qy6Ws3C9CRuaHpQx8AwuApbWkqnY> .
  biolink: pav:version "2.3.0" .
}