sub:assertion { d:DB00619dv:ddi-interactor-indr:DB00619_DB00864 . d:DB00864dv:ddi-interactor-indr:DB00619_DB00864 . dr:DB00619_DB00864dct:identifier "drugbank_resource:DB00619_DB00864" ; dct:title "DDI between Imatinib and Tacrolimus - The strong CYP3A4 inhibitor, Imatinib, may decrease the metabolism and clearance of Tacrolimus, a CYP3A4 substrate. Consider alternate therapy or monitor for changes in therapeutic and adverse effects of Tacrolimus if Imatinib is initiated, discontinued or dose changed."@en ; adv:Drug-Drug-Interaction ; rdfs:label "DDI between Imatinib and Tacrolimus - The strong CYP3A4 inhibitor, Imatinib, may decrease the metabolism and clearance of Tacrolimus, a CYP3A4 substrate. Consider alternate therapy or monitor for changes in therapeutic and adverse effects of Tacrolimus if Imatinib is initiated, discontinued or dose changed. [drugbank_resource:DB00619_DB00864]"@en . }