dgn-np:NP11112.RANkVZW4QE_QdL81KmtldUXkSj4jNl5cZpEH9T9aZsPW8130_provenance {
dgn-np:NP11112.RANkVZW4QE_QdL81KmtldUXkSj4jNl5cZpEH9T9aZsPW8130_assertion dcterms:description "[Here, through a genome-wide association study of rheumatoid arthritis, we identified a polymorphism in CCR6, the gene encoding chemokine (C-C motif) receptor 6 (a surface marker for Th17 cells) at 6q27, that was associated with rheumatoid arthritis susceptibility and was validated in two independent replication cohorts from Japan (rs3093024, a total of 7,069 individuals with rheumatoid arthritis (cases) and 20,727 controls, overall odds ratio = 1.19, P = 7.7 x 10(-19)).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en ;
wi:evidence dgn-void:source_evidence_curated ;
sio:SIO_000772 miriam-pubmed:20453841 ;
prov:wasDerivedFrom dgn-void:ctd_human-20130708 ;
prov:wasGeneratedBy eco:ECO_0000218 .
dgn-void:ctd_human-20130708 pav:importedOn "2013-07-24"^^
xsd:date .
dgn-void:source_evidence_curated a eco:ECO_0000205 ;
rdfs:comment "Gene-disease associations manually curated."@en ;
rdfs:label "DisGeNET evidence - CURATED"@en .
}