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All rights reserved. http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RANjRRoHZLP0VQq635pYsUdRQFKGAO6sLQE6BBltRb5XM#_6 http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/version 20131211 http://www.tkuhn.ch/bel2nanopub/RANjRRoHZLP0VQq635pYsUdRQFKGAO6sLQE6BBltRb5XM#_5 http://www.w3.org/ns/prov#value Furthermore, we show that inhibition of mTOR by rapamycin induces the activation of Akt as shown by increased Akt phosphorylation at Ser(473) and the inhibition of 6-TG-induced apoptosis and cell death. Activated Akt is a well-known inhibitor of autophagy. http://www.tkuhn.ch/bel2nanopub/RANjRRoHZLP0VQq635pYsUdRQFKGAO6sLQE6BBltRb5XM#_5 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/18381446 http://www.tkuhn.ch/bel2nanopub/RANjRRoHZLP0VQq635pYsUdRQFKGAO6sLQE6BBltRb5XM#_6 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RANjRRoHZLP0VQq635pYsUdRQFKGAO6sLQE6BBltRb5XM#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/18381446 http://www.tkuhn.ch/bel2nanopub/RANjRRoHZLP0VQq635pYsUdRQFKGAO6sLQE6BBltRb5XM#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RANjRRoHZLP0VQq635pYsUdRQFKGAO6sLQE6BBltRb5XM#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RANjRRoHZLP0VQq635pYsUdRQFKGAO6sLQE6BBltRb5XM#_5 http://www.tkuhn.ch/bel2nanopub/RANjRRoHZLP0VQq635pYsUdRQFKGAO6sLQE6BBltRb5XM#pubinfo http://www.tkuhn.ch/bel2nanopub/RANjRRoHZLP0VQq635pYsUdRQFKGAO6sLQE6BBltRb5XM http://purl.org/dc/terms/created 2014-07-03T14:33:19.852+02:00 http://www.tkuhn.ch/bel2nanopub/RANjRRoHZLP0VQq635pYsUdRQFKGAO6sLQE6BBltRb5XM http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RANjRRoHZLP0VQq635pYsUdRQFKGAO6sLQE6BBltRb5XM http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234