. . . . . . . . . . . . . . . . . . . . . . . . . . "kin(complex(SCOMP:\"p85/p110 PI3Kinase Complex\")) -> kin(p(SFAM:\"AKT Family\"))" . "kin(p(HGNC:PTK2)) -> (kin(complex(SCOMP:\"p85/p110 PI3Kinase Complex\")) -> kin(p(SFAM:\"AKT Family\")))" . "Approximately 61,000 statements." . "Copyright (c) 2011-2012, Selventa. All rights reserved." . "BEL Framework Large Corpus Document" . . "20131211" . "PI-3K-PKB/Akt. Integrins can activate the serine/ threonine kinase PKB/Akt in a PI-3K-dependent manner through FAK and integrin-linked kinase (ILK) [66,67]. For activation, PKB/Akt requires phosphatidyl inositol-3 phosphate-dependent translocation to the cell membrane and phosphorylation at two sites, 308T and 473S [68]. Activation of PKB/Akt by VEGF [69], insulin [70], or angiopoietin-1 [71] only occurs under conditions of integrin-dependent adhesion [72]" . . "Selventa" . . . . "2014-07-03T14:32:17.194+02:00"^^ . . .