@prefix this: . @prefix sub: . @prefix beldoc: . @prefix rdfs: . @prefix rdf: . @prefix xsd: . @prefix dct: . @prefix dce: . @prefix pav: . @prefix np: . @prefix belv: . @prefix prov: . @prefix Protein: . @prefix sfam: . @prefix geneProductOf: . @prefix go: . @prefix hgnc: . @prefix hasAgent: . @prefix obo: . @prefix occursIn: . @prefix species: . @prefix pubmed: . @prefix orcid: . sub:Head { this: np:hasAssertion sub:assertion; np:hasProvenance sub:provenance; np:hasPublicationInfo sub:pubinfo; a np:Nanopublication . } sub:assertion { sub:_1 geneProductOf: sfam:IFNA%20Family; a Protein: . sub:_2 hasAgent: sub:_3; a go:0042789 . sub:_3 geneProductOf: hgnc:11362; a Protein: . sub:_4 occursIn: obo:CL_0000235, species:9606; rdf:object sub:_2; rdf:predicate belv:increases; rdf:subject sub:_1; a rdf:Statement . sub:assertion rdfs:label "p(SFAM:\"IFNA Family\") -> tscript(p(HGNC:STAT1))" . } sub:provenance { beldoc: dce:description "Approximately 61,000 statements."; dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved."; dce:title "BEL Framework Large Corpus Document"; pav:authoredBy sub:_6; pav:version "20131211" . sub:_5 prov:value "from full text - IFN-a initiates the activation of STAT-1 followed by the induction of IFIG [35–37]. Although it is reported that IL-27 activates not only STAT-1, but also STAT-2, STAT-3, STAT-4 and STAT-5 in T cells [2,4,14,38], and activates STAT-3 in macrophages [39], it has not been clear whether the cytokine activates STAT-1 in macrophages. To determine whether IL-27 activates STAT-1 in CD4 T cells and MDM in our culture system, Western blot analysis was performed. The assay demonstrated that both cytokines induced the phosphorylation of STAT-1 in CD4 T cells and MDM (Fig. 2d)."; prov:wasQuotedFrom pubmed:18090390 . sub:_6 rdfs:label "Selventa" . sub:assertion prov:hadPrimarySource pubmed:18090390; prov:wasDerivedFrom beldoc:, sub:_5 . } sub:pubinfo { this: dct:created "2014-07-03T14:33:14.218+02:00"^^xsd:dateTime; pav:createdBy orcid:0000-0001-6818-334X, orcid:0000-0002-1267-0234 . }