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All rights reserved. http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAN2xZ9Wx8UND2r2gJWW5BO3K_SR5Z2jZC37pjkM2EslU#_3 http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/version 20131211 http://www.tkuhn.ch/bel2nanopub/RAN2xZ9Wx8UND2r2gJWW5BO3K_SR5Z2jZC37pjkM2EslU#_2 http://www.w3.org/ns/prov#value The capillary bed is known to be hyperpermeable in patients with sepsis, thereby leaking albumin. However, the extent to which altered liver biosynthesis and rates of catabolism contribute to the plasma albumin deficiency seen in sepsis and critical illness remains uncertain. Indeed, the half-life of HSA in patients with hypoalbuminemia supported with total parenteral nutrition is only 9 days, although rates of catabolism are normal.40 Moreover, catabolism actually may be decreased while the extracellular pool is increased, suggesting that HSA may be spared or protected. http://www.tkuhn.ch/bel2nanopub/RAN2xZ9Wx8UND2r2gJWW5BO3K_SR5Z2jZC37pjkM2EslU#_2 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/15915465 http://www.tkuhn.ch/bel2nanopub/RAN2xZ9Wx8UND2r2gJWW5BO3K_SR5Z2jZC37pjkM2EslU#_3 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RAN2xZ9Wx8UND2r2gJWW5BO3K_SR5Z2jZC37pjkM2EslU#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/15915465 http://www.tkuhn.ch/bel2nanopub/RAN2xZ9Wx8UND2r2gJWW5BO3K_SR5Z2jZC37pjkM2EslU#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RAN2xZ9Wx8UND2r2gJWW5BO3K_SR5Z2jZC37pjkM2EslU#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RAN2xZ9Wx8UND2r2gJWW5BO3K_SR5Z2jZC37pjkM2EslU#_2 http://www.tkuhn.ch/bel2nanopub/RAN2xZ9Wx8UND2r2gJWW5BO3K_SR5Z2jZC37pjkM2EslU#pubinfo http://www.tkuhn.ch/bel2nanopub/RAN2xZ9Wx8UND2r2gJWW5BO3K_SR5Z2jZC37pjkM2EslU http://purl.org/dc/terms/created 2014-07-03T14:32:45.257+02:00 http://www.tkuhn.ch/bel2nanopub/RAN2xZ9Wx8UND2r2gJWW5BO3K_SR5Z2jZC37pjkM2EslU http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RAN2xZ9Wx8UND2r2gJWW5BO3K_SR5Z2jZC37pjkM2EslU http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234