sub:assertion {
d:DB00864 dv:ddi-interactor-in dr:DB00864_DB00951 .
d:DB00951 dv:ddi-interactor-in dr:DB00864_DB00951 .
dr:DB00864_DB00951 dct:identifier "drugbank_resource:DB00864_DB00951" ;
dct:title "DDI between Tacrolimus and Isoniazid - The strong CYP3A4 inhibitor, Isoniazid, may decrease the metabolism and clearance of Tacrolimus, a CYP3A4 substrate. Consider alternate therapy or monitor for changes in therapeutic and adverse effects of Tacrolimus if Isoniazid is initiated, discontinued or dose changed."@en ;
a dv:Drug-Drug-Interaction ;
rdfs:label "DDI between Tacrolimus and Isoniazid - The strong CYP3A4 inhibitor, Isoniazid, may decrease the metabolism and clearance of Tacrolimus, a CYP3A4 substrate. Consider alternate therapy or monitor for changes in therapeutic and adverse effects of Tacrolimus if Isoniazid is initiated, discontinued or dose changed. [drugbank_resource:DB00864_DB00951]"@en .
}