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[Sepsis can be averted experimentally by endothelial cytoprotection through targeting nuclear signaling that mediates inflammation and deranged metabolism.Endothelial 'rheostats' (e.g. inhibitors of NF-?B, A20 protein, CRADD/RAIDD protein and microRNAs) regulate endothelial signaling.Physiologic 'extinguishers' (e.g. suppressor of cytokine signaling 3) can be replenished through intracellular protein therapy.Lipid mediators (e.g. resolvin D1) hasten sepsis resolution.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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