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[The gene most highly upregulated in A?-injected retinas was that for the chemokine CCL2, and its absence or that of its cognate receptor CCR2 greatly reduced migration of activated microglial cells to the site of retinal injury and profoundly worsened photoreceptor degeneration and disorganization of the retinal pigment epithelium in A?-injected retinas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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