sub:provenance { beldoc:dce:description "Approximately 61,000 statements." ; dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ; dce:title "BEL Framework Large Corpus Document" ; pav:authoredBysub:_5 ; pav:version "20131211" . sub:_4prov:value "xamination of the TGF{alpha} promoter sequence (Fig. 10Go) revealed the presence of both an octamer-like sequence between nt -610 and -603, and a downstream sequence between nt -596 and -587 similar to the TAATGARAT element in the HSV promoter, which has been shown to mediate inhibitory transcriptional effects of Oct-2 proteins (52, 63). Cotransfection of C6 cells with a reporter plasmid carrying a fragment of the TGF{alpha} promoter (-637 to +67) that contains both the octamer and the HSV-like motifs, and expression vectors containing either the Oct-2a or Oct-2c coding regions resulted in stimulation of the promoter’s activity (Fig. 10AGo). " ; prov:wasQuotedFrompubmed:10433239 . sub:_5rdfs:label "Selventa" . sub:assertionprov:hadPrimarySourcepubmed:10433239 ; prov:wasDerivedFrombeldoc: , sub:_4 . }