sub:assertion { d:DB00196dv:ddi-interactor-indr:DB00196_DB00440 . d:DB00440dv:ddi-interactor-indr:DB00196_DB00440 . dr:DB00196_DB00440dcterms:identifier "drugbank_resource:DB00196_DB00440" ; dcterms:title "DDI between Fluconazole and Trimethoprim - The strong CYP2C9 inhibitor, Fluconazole, may decrease the metabolism and clearance of Trimethoprim, a CYP2C9 substrate. Consider alternate therapy or monitor for changes in therapeutic and adverse effects of Trimethoprim if Fluconazole is initiated, discontinued or dose changed."@en ; adv:Drug-Drug-Interaction ; rdfs:label "DDI between Fluconazole and Trimethoprim - The strong CYP2C9 inhibitor, Fluconazole, may decrease the metabolism and clearance of Trimethoprim, a CYP2C9 substrate. Consider alternate therapy or monitor for changes in therapeutic and adverse effects of Trimethoprim if Fluconazole is initiated, discontinued or dose changed. [drugbank_resource:DB00196_DB00440]"@en . }