@prefix this: <
http://www.tkuhn.ch/bel2nanopub/RAMYNB_4Sm0PcxPK7EbI7vaJ6S3YF36b9HMVthrHn43GI
> .
@prefix sub: <
http://www.tkuhn.ch/bel2nanopub/RAMYNB_4Sm0PcxPK7EbI7vaJ6S3YF36b9HMVthrHn43GI#
> .
@prefix beldoc: <
http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel
> .
@prefix rdfs: <
http://www.w3.org/2000/01/rdf-schema#
> .
@prefix rdf: <
http://www.w3.org/1999/02/22-rdf-syntax-ns#
> .
@prefix xsd: <
http://www.w3.org/2001/XMLSchema#
> .
@prefix dct: <
http://purl.org/dc/terms/
> .
@prefix dce: <
http://purl.org/dc/elements/1.1/
> .
@prefix pav: <
http://purl.org/pav/
> .
@prefix np: <
http://www.nanopub.org/nschema#
> .
@prefix belv: <
http://www.selventa.com/vocabulary/
> .
@prefix prov: <
http://www.w3.org/ns/prov#
> .
@prefix go: <
http://amigo.geneontology.org/amigo/term/GO:
> .
@prefix Protein: <
http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080
> .
@prefix hgnc: <
http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=
> .
@prefix geneProductOf: <
http://purl.obolibrary.org/obo/RO_0002204
> .
@prefix hasAgent: <
http://semanticscience.org/resource/SIO_000139
> .
@prefix scomp: <
http://resource.belframework.org/belframework/20131211/namespace/selventa-named-complexes/
> .
@prefix ProteinComplex: <
http://amigo.geneontology.org/amigo/term/GO:0043234
> .
@prefix obo: <
http://purl.obolibrary.org/obo/
> .
@prefix occursIn: <
http://purl.obolibrary.org/obo/BFO_0000066
> .
@prefix species: <
http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=
> .
@prefix pubmed: <
http://www.ncbi.nlm.nih.gov/pubmed/
> .
@prefix orcid: <
http://orcid.org/
> .
sub:Head
{
this:
np:hasAssertion
sub:assertion
;
np:hasProvenance
sub:provenance
;
np:hasPublicationInfo
sub:pubinfo
;
a
np:Nanopublication
.
}
sub:assertion
{
scomp:p85%2Fp110%20PI3Kinase%20Complex
a
ProteinComplex:
.
sub:_1
hasAgent:
sub:_2
;
a
go:0016301
.
sub:_2
geneProductOf:
hgnc:4037
;
a
Protein:
.
sub:_3
hasAgent:
scomp:p85%2Fp110%20PI3Kinase%20Complex
;
a
go:0016301
.
sub:_4
occursIn:
obo:CL_0000097
,
species:9606
;
rdf:object
sub:_3
;
rdf:predicate
belv:increases
;
rdf:subject
sub:_1
;
a
rdf:Statement
.
sub:assertion
rdfs:label
"kin(p(HGNC:FYN)) -> kin(complex(SCOMP:\"p85/p110 PI3Kinase Complex\"))" .
}
sub:provenance
{
beldoc:
dce:description
"Approximately 61,000 statements." ;
dce:rights
"Copyright (c) 2011-2012, Selventa. All rights reserved." ;
dce:title
"BEL Framework Large Corpus Document" ;
pav:authoredBy
sub:_6
;
pav:version
"20131211" .
sub:_5
prov:value
"His group showed that, in addition to LYN, another SRC-family kinase, FYN, was also required for degranulation and cytokine production by activated mast cells20. This latter pathway did not require LAT and did not lead to the activation of PLCg but, instead, led to the activation of phosphatidylinositol 3-kinase (PI3K) downstream of the phosphorylation of the cytosolic adaptor molecule GAB2 (GRB2-associated binding protein 2)71 (TABLE 2; FIG. 4)." ;
prov:wasQuotedFrom
pubmed:16470226
.
sub:_6
rdfs:label
"Selventa" .
sub:assertion
prov:hadPrimarySource
pubmed:16470226
;
prov:wasDerivedFrom
beldoc:
,
sub:_5
.
}
sub:pubinfo
{
this:
dct:created
"2014-07-03T14:32:56.141+02:00"^^
xsd:dateTime
;
pav:createdBy
orcid:0000-0001-6818-334X
,
orcid:0000-0002-1267-0234
.
}