. . . . . . . . . . . . . . . . . "phos(p(HGNC:PTEN)) -| kin(complex(SCOMP:\"p85/p110 PI3Kinase Complex\"))" . "Approximately 61,000 statements." . "Copyright (c) 2011-2012, Selventa. All rights reserved." . "BEL Framework Large Corpus Document" . . "20131211" . "The P13K/Akt signalling pathway results in aggressive proliferation and is activated in most tumors, including gastric adenocarcinoma [107-109]. The tumor suppressor gene, pten (phosphatase and tensin homolog on chromosome ten), inhibits P13K function. Loss of pten expression is associated with P13/Akt signalling activation in many tumors. MiR-19a binds pten in vitro, and overexpression of miR-19 in lymphomas correlates with reduced expression of the Pten protein, thus overexpression of miR-19 in tumors could represent an alternative mechanism of activation of the P13K/Akt signalling pathway [58]." . . "Selventa" . . . . "2014-07-03T14:33:33.688+02:00"^^ . . .