@prefix this: <http://rdf.disgenet.org/resource/nanopub/NP300454.RAM9H1aAJYgJK0cXmVr5tquc1EOFmRmWMYrNxIRuUf0t0> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix sio: <http://semanticscience.org/resource/> .
@prefix ncit: <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#> .
@prefix lld: <http://linkedlifedata.com/resource/umls/id/> .
@prefix miriam-gene: <http://identifiers.org/ncbigene/> .
@prefix miriam-pubmed: <http://identifiers.org/pubmed/> .
@prefix eco: <http://purl.obolibrary.org/obo/> .
@prefix wi: <http://purl.org/ontology/wi/core#> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix pav: <http://purl.org/pav/> .
@prefix prv: <http://purl.org/net/provenance/ns#> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix dgn-np: <http://rdf.disgenet.org/resource/nanopub/> .
@prefix dgn-gda: <http://rdf.disgenet.org/resource/gda/> .
@prefix dgn-void: <http://rdf.disgenet.org/v4.0.0/void/> .

dgn-np:NP300454.RAM9H1aAJYgJK0cXmVr5tquc1EOFmRmWMYrNxIRuUf0t0130_head {
  this: np:hasAssertion dgn-np:NP300454.RAM9H1aAJYgJK0cXmVr5tquc1EOFmRmWMYrNxIRuUf0t0130_assertion;
    np:hasProvenance dgn-np:NP300454.RAM9H1aAJYgJK0cXmVr5tquc1EOFmRmWMYrNxIRuUf0t0130_provenance;
    np:hasPublicationInfo dgn-np:NP300454.RAM9H1aAJYgJK0cXmVr5tquc1EOFmRmWMYrNxIRuUf0t0130_publicationInfo;
    a np:Nanopublication .
  
  dgn-np:NP300454.RAM9H1aAJYgJK0cXmVr5tquc1EOFmRmWMYrNxIRuUf0t0130_assertion a np:Assertion .
  
  dgn-np:NP300454.RAM9H1aAJYgJK0cXmVr5tquc1EOFmRmWMYrNxIRuUf0t0130_provenance a np:Provenance .
  
  dgn-np:NP300454.RAM9H1aAJYgJK0cXmVr5tquc1EOFmRmWMYrNxIRuUf0t0130_publicationInfo a
      np:PublicationInfo .
}

dgn-np:NP300454.RAM9H1aAJYgJK0cXmVr5tquc1EOFmRmWMYrNxIRuUf0t0130_assertion {
  miriam-gene:5624 a ncit:C16612 .
  
  lld:C0546837 a ncit:C7057 .
  
  dgn-gda:DGNcce11d5c7ee57aa7e21aa4c74cdc609e sio:SIO_000628 miriam-gene:5624, lld:C0546837;
    a sio:SIO_001121 .
}

dgn-np:NP300454.RAM9H1aAJYgJK0cXmVr5tquc1EOFmRmWMYrNxIRuUf0t0130_provenance {
  dgn-np:NP300454.RAM9H1aAJYgJK0cXmVr5tquc1EOFmRmWMYrNxIRuUf0t0130_assertion dcterms:description
      "[Because hypermethylation of promoter regions is known to affect several other tumor suppressor genes, we investigated whether the APC promoter region is hypermethylated in esophageal cancer patients and whether this abnormality could serve as a prognostic plasma biomarker.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en;
    wi:evidence dgn-void:source_evidence_literature;
    sio:SIO_000772 miriam-pubmed:11078757;
    prov:wasDerivedFrom dgn-void:befree-2016;
    prov:wasGeneratedBy eco:ECO_0000203 .
  
  dgn-void:befree-2016 pav:importedOn "2016-02-19"^^xsd:date .
  
  dgn-void:source_evidence_literature a eco:ECO_0000212;
    rdfs:comment "Gene-disease associations inferred from text-mining the literature."@en;
    rdfs:label "DisGeNET evidence - LITERATURE"@en .
}

dgn-np:NP300454.RAM9H1aAJYgJK0cXmVr5tquc1EOFmRmWMYrNxIRuUf0t0130_publicationInfo {
  this: dcterms:created "2016-05-13T12:44:02+02:00"^^xsd:dateTime;
    dcterms:rights <http://opendatacommons.org/licenses/odbl/1.0/>;
    dcterms:rightsHolder dgn-void:IBIGroup;
    dcterms:subject sio:SIO_000983;
    prv:usedData dgn-void:disgenetv3.0rdf;
    pav:authoredBy <http://orcid.org/0000-0001-5999-6269>, <http://orcid.org/0000-0002-7534-7661>,
      <http://orcid.org/0000-0002-9383-528X>, <http://orcid.org/0000-0003-0169-8159>, <http://orcid.org/0000-0003-1244-7654>;
    pav:createdBy <http://orcid.org/0000-0003-0169-8159>;
    pav:version "v4.0.0.0" .
  
  dgn-void:disgenetv3.0rdf pav:version "v4.0.0" .
}