@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix this: <http://www.tkuhn.ch/bel2nanopub/RALze0gGdwXwDkbussx1gVuHUB6CtXJFOsy_nN2SENkbg> .
@prefix sub: <http://www.tkuhn.ch/bel2nanopub/RALze0gGdwXwDkbussx1gVuHUB6CtXJFOsy_nN2SENkbg#> .
@prefix beldoc: <http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix dce: <http://purl.org/dc/elements/1.1/> .
@prefix pav: <http://purl.org/pav/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix belv: <http://www.selventa.com/vocabulary/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix go: <http://amigo.geneontology.org/amigo/term/GO:> .
@prefix RNA: <http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_33697> .
@prefix hgnc: <http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=> .
@prefix geneProductOf: <http://purl.obolibrary.org/obo/RO_0002204> .
@prefix species: <http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=> .
@prefix occursIn: <http://purl.obolibrary.org/obo/BFO_0000066> .
@prefix obo: <http://purl.obolibrary.org/obo/> .
@prefix pubmed: <http://www.ncbi.nlm.nih.gov/pubmed/> .
@prefix orcid: <http://orcid.org/> .

sub:Head {
  this: np:hasAssertion sub:assertion;
    np:hasProvenance sub:provenance;
    np:hasPublicationInfo sub:pubinfo;
    a np:Nanopublication .
}

sub:assertion {
  sub:_1 geneProductOf: hgnc:939;
    a RNA: .
  
  sub:_2 occursIn: obo:UBERON_0000002, species:9606;
    rdf:object sub:_1;
    rdf:predicate belv:increases;
    rdf:subject go:0009408;
    a rdf:Statement .
  
  sub:assertion rdfs:label "bp(GOBP:\"response to heat\") -> r(HGNC:BAG3)" .
}

sub:provenance {
  beldoc: dce:description "Approximately 61,000 statements.";
    dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved.";
    dce:title "BEL Framework Large Corpus Document";
    pav:authoredBy sub:_4;
    pav:version "20131211" .
  
  sub:_3 prov:value "in hela cells the expression of the bag-3 gene, a member of the bag family, is regulated by heavy metals and temperature, with kinetics of accumulation of mrnas similar to hsp70 and metallothioneins. western blot assays performed with a polyclonal anti-bag-3 antibody confirmed that higher levels of the protein were present in the cells following heat and metal exposure. by immunofluorescence techniques and cell fractionation assays we demonstrated that following stress bag-3 protein concentrated in the rough endoplasmic reticulum and associated with the heavy membrane fraction. the role of bag-3 protein during apoptosis and cellular stress is discussed. in hela cells the expression of the bag-3 gene, a member of the bag family, is regulated by heavy metals and temperature, with kinetics of accumulation of mrnas similar to hsp70 and metallothioneins.";
    prov:wasQuotedFrom pubmed:12706811 .
  
  sub:_4 rdfs:label "Selventa" .
  
  sub:assertion prov:hadPrimarySource pubmed:12706811;
    prov:wasDerivedFrom beldoc:, sub:_3 .
}

sub:pubinfo {
  this: dcterms:created "2014-07-03T14:32:01.291+02:00"^^xsd:dateTime;
    pav:createdBy orcid:0000-0001-6818-334X, orcid:0000-0002-1267-0234 .
}