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a(CHEBI:glucocorticoid) -| tscript(complex(NCM:"Nfkb Complex"))
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Approximately 61,000 statements.
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Copyright (c) 2011-2012, Selventa. All rights reserved.
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BEL Framework Large Corpus Document
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1.4
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acidification or glucocorticoids increase the maximal activity and subunit mRNA levels of branched chain alpha-ketoacid dehydrogenase [BCKAD] in various cell types dexamethasone concurrently stimulated E2 subunit promoter activity and reduced the binding of nuclear factor-kappaB to a site in the E2 promoter thus acidification and glucocorticoids independently enhance BCKAD subunit gene expression, and the glucocorticoid repsonse in the E2 subunit involves interference with NF-kappaB, which may act as a transrepressor
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Selventa
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2014-07-03T14:29:55.333+02:00
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