@prefix this: . @prefix sub: . @prefix beldoc: . @prefix rdfs: . @prefix rdf: . @prefix xsd: . @prefix dct: . @prefix dce: . @prefix pav: . @prefix np: . @prefix belv: . @prefix prov: . @prefix go: . @prefix Protein: . @prefix mgi: . @prefix geneProductOf: . @prefix hasAgent: . @prefix RNA: . @prefix species: . @prefix occursIn: . @prefix mesh: . @prefix pubmed: . @prefix orcid: . sub:Head { this: np:hasAssertion sub:assertion; np:hasProvenance sub:provenance; np:hasPublicationInfo sub:pubinfo; a np:Nanopublication . } sub:assertion { sub:_1 hasAgent: sub:_2; a go:0042789 . sub:_2 geneProductOf: mgi:894659; a Protein: . sub:_3 geneProductOf: mgi:97283; a RNA: . sub:_4 occursIn: mesh:D018482, species:10090; rdf:object sub:_3; rdf:predicate belv:decreases; rdf:subject sub:_1; a rdf:Statement . sub:assertion rdfs:label "tscript(p(MGI:Hbp1)) -| r(MGI:Ncf1)" . } sub:provenance { beldoc: dce:description "Approximately 61,000 statements."; dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved."; dce:title "BEL Framework Large Corpus Document"; pav:authoredBy sub:_6; pav:version "1.4" . sub:_5 prov:value "In addition, Bar-Sagi and colleagues have shown that superoxide production is necessary for Rac-dependent G1 progression and cellular shape changes (Joneson and Bar-Sagi, 1998). Together, these and other observations highlight a role for ROS in growth factor signaling and mitogenesis. 2.3.2.2. HBP1 and the p47 phox gene As depicted in Fig. 5, we demonstrate that the transcriptional repressor HBP1 regulates the gene for the p47phox regulatory subunit of the NADPH oxidase. The promoter of the p47phox gene contains six tandem high-affinity HBP1 DNA binding elements at ?1243 to ?1318 bp from the transcriptional start site and which were required for repression. Furthermore, HBP1 repressed the expression of the endogenous p47phox gene through sequence-specific binding."; prov:wasQuotedFrom pubmed:15225871 . sub:_6 rdfs:label "Selventa" . sub:assertion prov:hadPrimarySource pubmed:15225871; prov:wasDerivedFrom beldoc:, sub:_5 . } sub:pubinfo { this: dct:created "2014-07-03T14:30:25.352+02:00"^^xsd:dateTime; pav:createdBy orcid:0000-0001-6818-334X, orcid:0000-0002-1267-0234 . }