. . . . . . . . . . . . . . . "kin(p(HGNC:TEK)) -> bp(GO:\"blood vessel development\")" . "Approximately 61,000 statements." . "Copyright (c) 2011-2012, Selventa. All rights reserved." . "BEL Framework Large Corpus Document" . . "1.4" . "Two other endothelial cell-specific receptors, called Tie-1 and Tie-2 (for \\\"tyrosine kinase with immunoglobulin- and EGF-like domains\\\") have been identified several years ago. Knock-out experiments in mice have suggested a role for these receptors in blood vessel maturation. The ligands for Tie-2 have only recently been discovered: angiopoietin-1 (Ang-1) and angiopoietin-2 (Ang-2) both bind Tie-2, but only the binding of Ang-1 results in signal transduction and regulation of blood vessel maturation (227). Therefore, Ang-2 is a natural antagonist of Ang-1 (146)." . . "Selventa" . . . . "2014-07-03T14:29:54.236+02:00"^^ . . .