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All rights reserved. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RALXxmuwdZPJWR-5V9yIHUCZ2O7BqceehYBiPccNyn-zQ#_7 http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/version 1.4 http://www.tkuhn.ch/bel2nanopub/RALXxmuwdZPJWR-5V9yIHUCZ2O7BqceehYBiPccNyn-zQ#_6 http://www.w3.org/ns/prov#value During vasculogenesis, angioblasts and early endothelial cells secrete into extracellular matrix Del1, which is a recently discovered ligand for avb3 involved in vascular remodeling (Hidai et al., 1998). In addition, ligation of this integrin complex also promotes a calcium influx required for endothelial motility (Leavesley et al., 1993). The expression of avb3 integrin is induced in microvascular endothelial cells by vascular endothelial growth factor-A (VEGF-A) (Senger et al., 1997), a highly specific activator of in vitro endothelial cell migration and proliferation and in vivo angiogenesis (Thomas, 1996; Ferrara and Davis-Smyth, 1997). http://www.tkuhn.ch/bel2nanopub/RALXxmuwdZPJWR-5V9yIHUCZ2O7BqceehYBiPccNyn-zQ#_6 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/10022831 http://www.tkuhn.ch/bel2nanopub/RALXxmuwdZPJWR-5V9yIHUCZ2O7BqceehYBiPccNyn-zQ#_7 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RALXxmuwdZPJWR-5V9yIHUCZ2O7BqceehYBiPccNyn-zQ#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/10022831 http://www.tkuhn.ch/bel2nanopub/RALXxmuwdZPJWR-5V9yIHUCZ2O7BqceehYBiPccNyn-zQ#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RALXxmuwdZPJWR-5V9yIHUCZ2O7BqceehYBiPccNyn-zQ#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RALXxmuwdZPJWR-5V9yIHUCZ2O7BqceehYBiPccNyn-zQ#_6 http://www.tkuhn.ch/bel2nanopub/RALXxmuwdZPJWR-5V9yIHUCZ2O7BqceehYBiPccNyn-zQ#pubinfo http://www.tkuhn.ch/bel2nanopub/RALXxmuwdZPJWR-5V9yIHUCZ2O7BqceehYBiPccNyn-zQ http://purl.org/dc/terms/created 2014-07-03T14:29:45.711+02:00 http://www.tkuhn.ch/bel2nanopub/RALXxmuwdZPJWR-5V9yIHUCZ2O7BqceehYBiPccNyn-zQ http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RALXxmuwdZPJWR-5V9yIHUCZ2O7BqceehYBiPccNyn-zQ http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234