sub:provenance {
beldoc: dce:description "Approximately 61,000 statements." ;
dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ;
dce:title "BEL Framework Large Corpus Document" ;
pav:authoredBy sub:_7 ;
pav:version "1.4" .
sub:_6 prov:value "During vasculogenesis, angioblasts and early endothelial cells secrete into extracellular matrix Del1, which is a recently discovered ligand for avb3 involved in vascular remodeling (Hidai et al., 1998). In addition, ligation of this integrin complex also promotes a calcium influx required for endothelial motility (Leavesley et al., 1993). The expression of avb3 integrin is induced in microvascular endothelial cells by vascular endothelial growth factor-A (VEGF-A) (Senger et al., 1997), a highly specific activator of in vitro endothelial cell migration and proliferation and in vivo angiogenesis (Thomas, 1996; Ferrara and Davis-Smyth, 1997)." ;
prov:wasQuotedFrom pubmed:10022831 .
sub:_7 rdfs:label "Selventa" .
sub:assertion prov:hadPrimarySource pubmed:10022831 ;
prov:wasDerivedFrom beldoc: ,
sub:_6 .
}