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All rights reserved. http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RALXLV_g4N58sY1ZcYrfx_aoDlGgYFfEz2aR11oJ1ckJc#_3 http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/version 20131211 http://www.tkuhn.ch/bel2nanopub/RALXLV_g4N58sY1ZcYrfx_aoDlGgYFfEz2aR11oJ1ckJc#_2 http://www.w3.org/ns/prov#value Several parameters were evaluated to confirm that treatment of primary cultures of both HTM and HDF cells with H2O2 (200 uM) twice a day for four days induced a senescent phenotype. This treatment resulted in significant increases in SA-?-gal activity, autofluorescence, and endogenous ROS production.....There was also a significant decrease in cell proliferation rate quantified by BrdU incorporation. http://www.tkuhn.ch/bel2nanopub/RALXLV_g4N58sY1ZcYrfx_aoDlGgYFfEz2aR11oJ1ckJc#_2 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/19782699 http://www.tkuhn.ch/bel2nanopub/RALXLV_g4N58sY1ZcYrfx_aoDlGgYFfEz2aR11oJ1ckJc#_3 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RALXLV_g4N58sY1ZcYrfx_aoDlGgYFfEz2aR11oJ1ckJc#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/19782699 http://www.tkuhn.ch/bel2nanopub/RALXLV_g4N58sY1ZcYrfx_aoDlGgYFfEz2aR11oJ1ckJc#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RALXLV_g4N58sY1ZcYrfx_aoDlGgYFfEz2aR11oJ1ckJc#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RALXLV_g4N58sY1ZcYrfx_aoDlGgYFfEz2aR11oJ1ckJc#_2 http://www.tkuhn.ch/bel2nanopub/RALXLV_g4N58sY1ZcYrfx_aoDlGgYFfEz2aR11oJ1ckJc#pubinfo http://www.tkuhn.ch/bel2nanopub/RALXLV_g4N58sY1ZcYrfx_aoDlGgYFfEz2aR11oJ1ckJc http://purl.org/dc/terms/created 2014-07-03T14:33:37.326+02:00 http://www.tkuhn.ch/bel2nanopub/RALXLV_g4N58sY1ZcYrfx_aoDlGgYFfEz2aR11oJ1ckJc http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RALXLV_g4N58sY1ZcYrfx_aoDlGgYFfEz2aR11oJ1ckJc http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234