. . . . . . . . . . . . "[Many characterological depressives (outpatients with early insidious onset and fluctuating chronicity of subthreshold manifestations falling short of full syndromal depression), were shown to have shortened REM latency, increased REM%, redistribution of REM to the first part of the night, classic diurnality, high rates of family history for mood disorders, positive response to antidepressants and sleep deprivation, and prospective follow-up course leading to major affective episodes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en . . . . . "2014-02-25"^^ . . "Gene-disease associations inferred from text-mining the literature."@en . "DisGeNET evidence - LITERATURE"@en . "2014-10-02T12:33:25+02:00"^^ . . . . . . . . . . . "v2.1.0.0" . "v2.1.0" .