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All rights reserved. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RALFtxrRm8gSDON-AERAVzbpmgbhBJZr_dMf61Av9XGBA#_7 http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/version 1.4 http://www.tkuhn.ch/bel2nanopub/RALFtxrRm8gSDON-AERAVzbpmgbhBJZr_dMf61Av9XGBA#_6 http://www.w3.org/ns/prov#value Treatment of IKK2 mutant macrophages with lippolysaccharides (LPS, an activator of IKBKB activity) showed approximately 40-50% less p65 activation at 10 and 60 minutes, respectively when compared with control. In addition, immunocytochemistry revealed that approximately 20% of IKK2 deleted cells did not show nuclear translocation of p65 after LPS stimulation, whereas control showed >95% translocation. 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