[ {
  "@graph" : [ {
    "@id" : "http://www.tkuhn.ch/bel2nanopub/RAL6nM9E9DZL7APEO1uGzYNs088-eYm4kMnyrNuEr6nfg",
    "@type" : [ "http://www.nanopub.org/nschema#Nanopublication" ],
    "http://www.nanopub.org/nschema#hasAssertion" : [ {
      "@id" : "http://www.tkuhn.ch/bel2nanopub/RAL6nM9E9DZL7APEO1uGzYNs088-eYm4kMnyrNuEr6nfg#assertion"
    } ],
    "http://www.nanopub.org/nschema#hasProvenance" : [ {
      "@id" : "http://www.tkuhn.ch/bel2nanopub/RAL6nM9E9DZL7APEO1uGzYNs088-eYm4kMnyrNuEr6nfg#provenance"
    } ],
    "http://www.nanopub.org/nschema#hasPublicationInfo" : [ {
      "@id" : "http://www.tkuhn.ch/bel2nanopub/RAL6nM9E9DZL7APEO1uGzYNs088-eYm4kMnyrNuEr6nfg#pubinfo"
    } ]
  } ],
  "@id" : "http://www.tkuhn.ch/bel2nanopub/RAL6nM9E9DZL7APEO1uGzYNs088-eYm4kMnyrNuEr6nfg#Head"
}, {
  "@graph" : [ {
    "@id" : "http://www.tkuhn.ch/bel2nanopub/RAL6nM9E9DZL7APEO1uGzYNs088-eYm4kMnyrNuEr6nfg#_1",
    "@type" : [ "http://amigo.geneontology.org/amigo/term/GO:0042789" ],
    "http://semanticscience.org/resource/SIO_000139" : [ {
      "@id" : "http://www.tkuhn.ch/bel2nanopub/RAL6nM9E9DZL7APEO1uGzYNs088-eYm4kMnyrNuEr6nfg#_2"
    } ]
  }, {
    "@id" : "http://www.tkuhn.ch/bel2nanopub/RAL6nM9E9DZL7APEO1uGzYNs088-eYm4kMnyrNuEr6nfg#_2",
    "@type" : [ "http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080" ],
    "http://purl.obolibrary.org/obo/RO_0002204" : [ {
      "@id" : "http://rgd.mcw.edu/rgdweb/report/gene/main.html?id=1304603"
    } ]
  }, {
    "@id" : "http://www.tkuhn.ch/bel2nanopub/RAL6nM9E9DZL7APEO1uGzYNs088-eYm4kMnyrNuEr6nfg#_3",
    "@type" : [ "http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement" ],
    "http://purl.obolibrary.org/obo/BFO_0000066" : [ {
      "@id" : "http://purl.bioontology.org/ontology/MSH/D018482"
    }, {
      "@id" : "http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=10116"
    } ],
    "http://www.w3.org/1999/02/22-rdf-syntax-ns#object" : [ {
      "@id" : "http://www.tkuhn.ch/bel2nanopub/RAL6nM9E9DZL7APEO1uGzYNs088-eYm4kMnyrNuEr6nfg#_1"
    } ],
    "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate" : [ {
      "@id" : "http://www.selventa.com/vocabulary/increases"
    } ],
    "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject" : [ {
      "@id" : "http://purl.bioontology.org/ontology/MSH/D015444"
    } ]
  }, {
    "@id" : "http://www.tkuhn.ch/bel2nanopub/RAL6nM9E9DZL7APEO1uGzYNs088-eYm4kMnyrNuEr6nfg#assertion",
    "http://www.w3.org/2000/01/rdf-schema#label" : [ {
      "@value" : "bp(MESHPP:Exercise) -> tscript(p(RGD:Nrf1))"
    } ]
  } ],
  "@id" : "http://www.tkuhn.ch/bel2nanopub/RAL6nM9E9DZL7APEO1uGzYNs088-eYm4kMnyrNuEr6nfg#assertion"
}, {
  "@graph" : [ {
    "@id" : "http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel",
    "http://purl.org/dc/elements/1.1/description" : [ {
      "@value" : "Approximately 61,000 statements."
    } ],
    "http://purl.org/dc/elements/1.1/rights" : [ {
      "@value" : "Copyright (c) 2011-2012, Selventa. All rights reserved."
    } ],
    "http://purl.org/dc/elements/1.1/title" : [ {
      "@value" : "BEL Framework Large Corpus Document"
    } ],
    "http://purl.org/pav/authoredBy" : [ {
      "@id" : "http://www.tkuhn.ch/bel2nanopub/RAL6nM9E9DZL7APEO1uGzYNs088-eYm4kMnyrNuEr6nfg#_5"
    } ],
    "http://purl.org/pav/version" : [ {
      "@value" : "1.4"
    } ]
  }, {
    "@id" : "http://www.tkuhn.ch/bel2nanopub/RAL6nM9E9DZL7APEO1uGzYNs088-eYm4kMnyrNuEr6nfg#_4",
    "http://www.w3.org/ns/prov#value" : [ {
      "@value" : "The magnitude of this increase was twofold (Fig. 3). An increase in PGC-1 protein of similar magnitude was seen 18 h after the fifth bout of exercise (data not shown). This finding is important because increases in mRNA do not always result in a parallel increase in protein. There was an increase in a smaller protein, which, like the full-length form, was completely competed away with a PGC-1 blocking peptide. The size of this smaller PGC-1 protein (34 kDa) is consistent with that of the smaller PGC-1 mRNA, which appears to be missing exon 8. Antibodies directed at the amino terminus (Fig. 3A) and the carboxyl terminus (Fig. 3A) recognized the shorter PGC-1 protein. It will be interesting to determine whether this smaller PGC-1 protein is in fact the translation product of the shortened PGC-1 mRNA and whether it has functional significance. Effect of exercise on expression of NRF-1 and NRF-2 NRF-1 protein binding was detected by electrophoretic mobility shift assay using an oligonucleotide containing a NRF-1 binding site from the ALA synthase promoter. NRF-2 protein binding was determined using an oligonucleotide containing the NRF-2 protein-binding site from the cytochrome oxidase subunit IV promoter. The NRF-1-specific band is shown by the arrow in Fig. 4A; quantitative analysis is shown in Fig. 4C. There was a 50% increase in NRF-1 binding in eight of nine muscles 18 h after the exercise; in other muscle, an increase was evident 12 h after exercise. This finding of an increase in NRF-1 DNA binding is in keeping with the observation of Murakami et al. (37) of a 50% increase in NRF-1 mRNA in soleus muscle of rats 6 h after a bout of running."
    } ],
    "http://www.w3.org/ns/prov#wasQuotedFrom" : [ {
      "@id" : "http://www.ncbi.nlm.nih.gov/pubmed/12468452"
    } ]
  }, {
    "@id" : "http://www.tkuhn.ch/bel2nanopub/RAL6nM9E9DZL7APEO1uGzYNs088-eYm4kMnyrNuEr6nfg#_5",
    "http://www.w3.org/2000/01/rdf-schema#label" : [ {
      "@value" : "Selventa"
    } ]
  }, {
    "@id" : "http://www.tkuhn.ch/bel2nanopub/RAL6nM9E9DZL7APEO1uGzYNs088-eYm4kMnyrNuEr6nfg#assertion",
    "http://www.w3.org/ns/prov#hadPrimarySource" : [ {
      "@id" : "http://www.ncbi.nlm.nih.gov/pubmed/12468452"
    } ],
    "http://www.w3.org/ns/prov#wasDerivedFrom" : [ {
      "@id" : "http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel"
    }, {
      "@id" : "http://www.tkuhn.ch/bel2nanopub/RAL6nM9E9DZL7APEO1uGzYNs088-eYm4kMnyrNuEr6nfg#_4"
    } ]
  } ],
  "@id" : "http://www.tkuhn.ch/bel2nanopub/RAL6nM9E9DZL7APEO1uGzYNs088-eYm4kMnyrNuEr6nfg#provenance"
}, {
  "@graph" : [ {
    "@id" : "http://www.tkuhn.ch/bel2nanopub/RAL6nM9E9DZL7APEO1uGzYNs088-eYm4kMnyrNuEr6nfg",
    "http://purl.org/dc/terms/created" : [ {
      "@type" : "http://www.w3.org/2001/XMLSchema#dateTime",
      "@value" : "2014-07-03T14:30:07.704+02:00"
    } ],
    "http://purl.org/pav/createdBy" : [ {
      "@id" : "http://orcid.org/0000-0001-6818-334X"
    }, {
      "@id" : "http://orcid.org/0000-0002-1267-0234"
    } ]
  } ],
  "@id" : "http://www.tkuhn.ch/bel2nanopub/RAL6nM9E9DZL7APEO1uGzYNs088-eYm4kMnyrNuEr6nfg#pubinfo"
} ]