@prefix this: <http://rdf.disgenet.org/resource/nanopub/NP621144.RAKm5xUcK6XyASZbVxivzoWIO8rer9_AkTvgE4VLkkWiQ> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix sio: <http://semanticscience.org/resource/> .
@prefix ncit: <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#> .
@prefix lld: <http://linkedlifedata.com/resource/umls/id/> .
@prefix miriam-gene: <http://identifiers.org/ncbigene/> .
@prefix miriam-pubmed: <http://identifiers.org/pubmed/> .
@prefix eco: <http://purl.obolibrary.org/obo/> .
@prefix wi: <http://purl.org/ontology/wi/core#> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix pav: <http://purl.org/pav/> .
@prefix prv: <http://purl.org/net/provenance/ns#> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix dgn-np: <http://rdf.disgenet.org/resource/nanopub/> .
@prefix dgn-gda: <http://rdf.disgenet.org/resource/gda/> .
@prefix dgn-void: <http://rdf.disgenet.org/v3.0.0/void/> .

dgn-np:NP621144.RAKm5xUcK6XyASZbVxivzoWIO8rer9_AkTvgE4VLkkWiQ130_head {
  this: np:hasAssertion dgn-np:NP621144.RAKm5xUcK6XyASZbVxivzoWIO8rer9_AkTvgE4VLkkWiQ130_assertion;
    np:hasProvenance dgn-np:NP621144.RAKm5xUcK6XyASZbVxivzoWIO8rer9_AkTvgE4VLkkWiQ130_provenance;
    np:hasPublicationInfo dgn-np:NP621144.RAKm5xUcK6XyASZbVxivzoWIO8rer9_AkTvgE4VLkkWiQ130_publicationInfo;
    a np:Nanopublication .
  
  dgn-np:NP621144.RAKm5xUcK6XyASZbVxivzoWIO8rer9_AkTvgE4VLkkWiQ130_assertion a np:Assertion .
  
  dgn-np:NP621144.RAKm5xUcK6XyASZbVxivzoWIO8rer9_AkTvgE4VLkkWiQ130_provenance a np:Provenance .
  
  dgn-np:NP621144.RAKm5xUcK6XyASZbVxivzoWIO8rer9_AkTvgE4VLkkWiQ130_publicationInfo a
      np:PublicationInfo .
}

dgn-np:NP621144.RAKm5xUcK6XyASZbVxivzoWIO8rer9_AkTvgE4VLkkWiQ130_assertion {
  miriam-gene:5290 a ncit:C16612 .
  
  lld:C0025202 a ncit:C7057 .
  
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    a sio:SIO_001121 .
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dgn-np:NP621144.RAKm5xUcK6XyASZbVxivzoWIO8rer9_AkTvgE4VLkkWiQ130_provenance {
  dgn-np:NP621144.RAKm5xUcK6XyASZbVxivzoWIO8rer9_AkTvgE4VLkkWiQ130_assertion dcterms:description
      "[Although activation of the PI3K/Akt pathway resulting from genetic mutations and epigenetic deregulation of its major regulators is known to cause resistance of melanoma to therapeutic agents, including the conventional chemotherapeutic drug dacarbazine and the Food and Drug Administration-approved mutant BRAF inhibitors vemurafenib and dabrafenib, the role of extracellular stimuli of the pathway, such as insulin, in drug resistance of melanoma remains less understood.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en;
    wi:evidence dgn-void:source_evidence_literature;
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    prov:wasDerivedFrom dgn-void:befree-20150227;
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  dgn-void:befree-20150227 pav:importedOn "2015-02-27"^^xsd:date .
  
  dgn-void:source_evidence_literature a eco:ECO_0000212;
    rdfs:comment "Gene-disease associations inferred from text-mining the literature."@en;
    rdfs:label "DisGeNET evidence - LITERATURE"@en .
}

dgn-np:NP621144.RAKm5xUcK6XyASZbVxivzoWIO8rer9_AkTvgE4VLkkWiQ130_publicationInfo {
  this: dcterms:created "2015-08-25T14:43:51+02:00"^^xsd:dateTime;
    dcterms:rights <http://opendatacommons.org/licenses/odbl/1.0/>;
    dcterms:rightsHolder dgn-void:IBIGroup;
    dcterms:subject sio:SIO_000983;
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    pav:authoredBy <http://orcid.org/0000-0001-5999-6269>, <http://orcid.org/0000-0002-7534-7661>,
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    pav:createdBy <http://orcid.org/0000-0003-0169-8159>;
    pav:version "v3.0.0.0" .
  
  dgn-void:disgenetv3.0rdf pav:version "v3.0.0" .
}