sub:assertion {
d:DB00176 dv:ddi-interactor-in dr:DB00176_DB01142 .
d:DB01142 dv:ddi-interactor-in dr:DB00176_DB01142 .
dr:DB00176_DB01142 dct:identifier "drugbank_resource:DB00176_DB01142" ;
dct:title "DDI between Fluvoxamine and Doxepin - The SSRI, fluvoxamine, may increase the serum concentration of the tricyclic antidepressant, doxepin, by decreasing its metabolism. Additive modulation of serotonin activity also increases the risk of serotonin syndrome. Monitor for development of serotonin syndrome during concomitant therapy. Monitor for changes in the therapeutic and adverse effects of doxepin if fluvoxamine is initiated, discontinued or dose changed."@en ;
a dv:Drug-Drug-Interaction ;
rdfs:label "DDI between Fluvoxamine and Doxepin - The SSRI, fluvoxamine, may increase the serum concentration of the tricyclic antidepressant, doxepin, by decreasing its metabolism. Additive modulation of serotonin activity also increases the risk of serotonin syndrome. Monitor for development of serotonin syndrome during concomitant therapy. Monitor for changes in the therapeutic and adverse effects of doxepin if fluvoxamine is initiated, discontinued or dose changed. [drugbank_resource:DB00176_DB01142]"@en .
}