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[Using basal forebrain cholinergic neurons (BFCNs) as a model and immunohistochemistry, we have demonstrated significant age-related loss of the calcium-binding protein calbindin-D(28K) (CB) from BFCN, which was associated with tangle formation and degeneration in AD.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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