. . . . . . . . . . . . . . . "p(MGI:Hipk2) -| p(MGI:Ccnd1)" . "Approximately 61,000 statements." . "Copyright (c) 2011-2012, Selventa. All rights reserved." . "BEL Framework Large Corpus Document" . . "20131211" . "Although cyclin E, cdk4, cdk6, p16, and p21 showed no detectable difference between WT and Hipk2?/? MEFs, the level of cyclin D1 protein was up-regulated in Hipk2?/? MEFs and keratinocytes by 2.5- and 3-fold, respectively. FROM TEXT: Given the role of HIPK2 as a transcriptional corepressor, we reasoned that an increase in cyclin D1 protein may be due to an increase in transcription of cyclin D1 in Hipk2?/? MEFs. Consistent with this, quantitative RT-PCR (qRT-PCR) showed that cyclin D1 mRNA, but not D2 or D3, was up-regulated in Hipk2?/? MEFs." . . "Selventa" . . . . "2014-07-03T14:33:12.080+02:00"^^ . . .