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[Our findings, also supported by the ?-amyloid plasma assay, confirm (1) the pathogenic role of the APP A713T mutation, (2) the specific phenotype (AD with cerebrovascular lesions) associated with this mutation, and (3) the large span of age at onset, not influenced by APOE, TOMM40, and TREM2 genes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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