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[Nonspecific orofacial symptoms were associated with voltage-gated sodium channel, type I, alpha subunit (SCN1A, rs6432860, P = 2.77 � 10(-5)) and angiotensin I-converting enzyme 2 (ACE2, rs1514280, P = 4.86 � 10(-5)); global psychological symptoms with prostaglandin-endoperoxide synthase 1 (PTGS1, rs3842803, P = 2.79 � 10(-6)); stress and negative affectivity with amyloid-? (A4) precursor protein (APP, rs466448, P = 4.29 � 10(-5)); and heat pain temporal summation with multiple PDZ domain protein (MPDZ, rs10809907, P = 3.05 � 10(-5)).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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