http://www.tkuhn.ch/bel2nanopub/RAJYra00rTqWZQ5lb-fcxZyspfTDn9j7vCKJtMCQtjrVc#Head http://www.tkuhn.ch/bel2nanopub/RAJYra00rTqWZQ5lb-fcxZyspfTDn9j7vCKJtMCQtjrVc http://www.nanopub.org/nschema#hasAssertion http://www.tkuhn.ch/bel2nanopub/RAJYra00rTqWZQ5lb-fcxZyspfTDn9j7vCKJtMCQtjrVc#assertion http://www.tkuhn.ch/bel2nanopub/RAJYra00rTqWZQ5lb-fcxZyspfTDn9j7vCKJtMCQtjrVc http://www.nanopub.org/nschema#hasProvenance http://www.tkuhn.ch/bel2nanopub/RAJYra00rTqWZQ5lb-fcxZyspfTDn9j7vCKJtMCQtjrVc#provenance http://www.tkuhn.ch/bel2nanopub/RAJYra00rTqWZQ5lb-fcxZyspfTDn9j7vCKJtMCQtjrVc http://www.nanopub.org/nschema#hasPublicationInfo http://www.tkuhn.ch/bel2nanopub/RAJYra00rTqWZQ5lb-fcxZyspfTDn9j7vCKJtMCQtjrVc#pubinfo http://www.tkuhn.ch/bel2nanopub/RAJYra00rTqWZQ5lb-fcxZyspfTDn9j7vCKJtMCQtjrVc http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication http://www.tkuhn.ch/bel2nanopub/RAJYra00rTqWZQ5lb-fcxZyspfTDn9j7vCKJtMCQtjrVc#assertion http://www.tkuhn.ch/bel2nanopub/RAJYra00rTqWZQ5lb-fcxZyspfTDn9j7vCKJtMCQtjrVc#_1 http://purl.obolibrary.org/obo/RO_0002204 http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=12556 http://www.tkuhn.ch/bel2nanopub/RAJYra00rTqWZQ5lb-fcxZyspfTDn9j7vCKJtMCQtjrVc#_1 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_33697 http://www.tkuhn.ch/bel2nanopub/RAJYra00rTqWZQ5lb-fcxZyspfTDn9j7vCKJtMCQtjrVc#_2 http://purl.obolibrary.org/obo/BFO_0000066 http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=9606 http://www.tkuhn.ch/bel2nanopub/RAJYra00rTqWZQ5lb-fcxZyspfTDn9j7vCKJtMCQtjrVc#_2 http://www.w3.org/1999/02/22-rdf-syntax-ns#object http://www.tkuhn.ch/bel2nanopub/RAJYra00rTqWZQ5lb-fcxZyspfTDn9j7vCKJtMCQtjrVc#_1 http://www.tkuhn.ch/bel2nanopub/RAJYra00rTqWZQ5lb-fcxZyspfTDn9j7vCKJtMCQtjrVc#_2 http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate http://www.selventa.com/vocabulary/decreases http://www.tkuhn.ch/bel2nanopub/RAJYra00rTqWZQ5lb-fcxZyspfTDn9j7vCKJtMCQtjrVc#_2 http://www.w3.org/1999/02/22-rdf-syntax-ns#subject http://purl.bioontology.org/ontology/MSH/D017209 http://www.tkuhn.ch/bel2nanopub/RAJYra00rTqWZQ5lb-fcxZyspfTDn9j7vCKJtMCQtjrVc#_2 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement http://www.tkuhn.ch/bel2nanopub/RAJYra00rTqWZQ5lb-fcxZyspfTDn9j7vCKJtMCQtjrVc#assertion http://www.w3.org/2000/01/rdf-schema#label bp(MESHPP:Apoptosis) -| r(HGNC:UHRF1) http://www.tkuhn.ch/bel2nanopub/RAJYra00rTqWZQ5lb-fcxZyspfTDn9j7vCKJtMCQtjrVc#provenance http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/description Approximately 61,000 statements. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/rights Copyright (c) 2011-2012, Selventa. All rights reserved. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAJYra00rTqWZQ5lb-fcxZyspfTDn9j7vCKJtMCQtjrVc#_4 http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/version 1.4 http://www.tkuhn.ch/bel2nanopub/RAJYra00rTqWZQ5lb-fcxZyspfTDn9j7vCKJtMCQtjrVc#_3 http://www.w3.org/ns/prov#value Inhibition of apoptosis, resulting from an increase in anti-apoptotic protein, plays a fundamental role in carcinogenesis. Because ICBP90 gene expression is deregulated in cancer cells, we studied its expression in Jurkat cells under apoptotic conditions to see whether ICBP90 is involved in the regulation of apoptosis. We found that ICBP90 expression and the percentage of living cells were dose-dependently decreased in PHA and ionophore A23187-stimulated Jurkat cells, but not in THP-1 cells. These results suggest that apoptosis is dependent upon ICBP90 expression downregulation and that ICBP90 exhibits anti-apoptotic properties. http://www.tkuhn.ch/bel2nanopub/RAJYra00rTqWZQ5lb-fcxZyspfTDn9j7vCKJtMCQtjrVc#_3 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/15033738 http://www.tkuhn.ch/bel2nanopub/RAJYra00rTqWZQ5lb-fcxZyspfTDn9j7vCKJtMCQtjrVc#_4 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RAJYra00rTqWZQ5lb-fcxZyspfTDn9j7vCKJtMCQtjrVc#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/15033738 http://www.tkuhn.ch/bel2nanopub/RAJYra00rTqWZQ5lb-fcxZyspfTDn9j7vCKJtMCQtjrVc#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RAJYra00rTqWZQ5lb-fcxZyspfTDn9j7vCKJtMCQtjrVc#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RAJYra00rTqWZQ5lb-fcxZyspfTDn9j7vCKJtMCQtjrVc#_3 http://www.tkuhn.ch/bel2nanopub/RAJYra00rTqWZQ5lb-fcxZyspfTDn9j7vCKJtMCQtjrVc#pubinfo http://www.tkuhn.ch/bel2nanopub/RAJYra00rTqWZQ5lb-fcxZyspfTDn9j7vCKJtMCQtjrVc http://purl.org/dc/terms/created 2014-07-03T14:30:21.700+02:00 http://www.tkuhn.ch/bel2nanopub/RAJYra00rTqWZQ5lb-fcxZyspfTDn9j7vCKJtMCQtjrVc http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RAJYra00rTqWZQ5lb-fcxZyspfTDn9j7vCKJtMCQtjrVc http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234