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All rights reserved. http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAJRG81KPMgShu98Wt4Ls-2cy5XSeYoQbxfsrRdiOZw38#_5 http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/version 20131211 http://www.tkuhn.ch/bel2nanopub/RAJRG81KPMgShu98Wt4Ls-2cy5XSeYoQbxfsrRdiOZw38#_4 http://www.w3.org/ns/prov#value When muscle is placed under stress or is damaged, the CRPs might signal to the nucleus to initiate repair through the activation ofmuscle-specific genes. In support of this hypothesis, CRP3/MLP seems to be a component of a Z-disc-localized stress sensor in cardiomyocytes, which, when it is defective, leads to the development of human dilated cardiomyopathy81. 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