. . . . . . . . . . . . . "cat(p(PFH:\"PDE4 Family\")) -| a(SCHEM:\"cyclic AMP\")" . "Approximately 61,000 statements." . "Copyright (c) 2011-2012, Selventa. All rights reserved." . "BEL Framework Large Corpus Document" . . "1.4" . "We also show that activation of extracellular signal-regulated kinase (Erk) by BDNF is required to overcome inhibition by MAG, and that activated Erk transiently inhibits phosphodiesterase 4 (PDE4), the enzyme that hydrolyzes cAMP. Inhibition of PDE4 then allows cAMP to increase and so initiates the pathway to overcome inhibition." . . "Selventa" . . . . "2014-07-03T14:30:19.221+02:00"^^ . . .