. . . . . . . . . . . . . "p(MGI:Tnf) -> p(MGI:Ptgs2)" . "Approximately 61,000 statements." . "Copyright (c) 2011-2012, Selventa. All rights reserved." . "BEL Framework Large Corpus Document" . . "1.4" . "Treatment of cells with both IL-1 alpha and TNF-alpha resulted in markedly up regulation of COX-2 mRNA and PGE2. The increase in PGE2 production by IL-1 alpha and TNF-alpha was significantly suppressed by aminoguanidine and aspirin, a selective inhibitors of iNOS and COX-2. This indicates that COX-2 mediates the PGE-2 production and nitric oxide potentiates the PGE-2 production." . . "Selventa" . . . . "2014-07-03T14:30:59.055+02:00"^^ . . .