@prefix this: . @prefix rdfs: . @prefix xsd: . @prefix sio: . @prefix ncit: . @prefix lld: . @prefix miriam-gene: . @prefix miriam-pubmed: . @prefix eco: . @prefix wi: . @prefix prov: . @prefix pav: . @prefix prv: . @prefix dcterms: . @prefix np: . @prefix dgn-np: . @prefix dgn-gda: . @prefix dgn-void: . dgn-np:NP428752.RAIg2QCCoOv5WPYzxxf-zTO7aSln3HJwRV3dFv0VDHZDI130_head { this: np:hasAssertion dgn-np:NP428752.RAIg2QCCoOv5WPYzxxf-zTO7aSln3HJwRV3dFv0VDHZDI130_assertion; np:hasProvenance dgn-np:NP428752.RAIg2QCCoOv5WPYzxxf-zTO7aSln3HJwRV3dFv0VDHZDI130_provenance; np:hasPublicationInfo dgn-np:NP428752.RAIg2QCCoOv5WPYzxxf-zTO7aSln3HJwRV3dFv0VDHZDI130_publicationInfo; a np:Nanopublication . dgn-np:NP428752.RAIg2QCCoOv5WPYzxxf-zTO7aSln3HJwRV3dFv0VDHZDI130_assertion a np:Assertion . dgn-np:NP428752.RAIg2QCCoOv5WPYzxxf-zTO7aSln3HJwRV3dFv0VDHZDI130_provenance a np:Provenance . dgn-np:NP428752.RAIg2QCCoOv5WPYzxxf-zTO7aSln3HJwRV3dFv0VDHZDI130_publicationInfo a np:PublicationInfo . } dgn-np:NP428752.RAIg2QCCoOv5WPYzxxf-zTO7aSln3HJwRV3dFv0VDHZDI130_assertion { miriam-gene:7046 a ncit:C16612 . lld:C0006826 a ncit:C7057 . dgn-gda:DGNd2bd1f6c3b45da4842ab6a246c6351ce sio:SIO_000628 miriam-gene:7046, lld:C0006826; a sio:SIO_001121 . } dgn-np:NP428752.RAIg2QCCoOv5WPYzxxf-zTO7aSln3HJwRV3dFv0VDHZDI130_provenance { dgn-np:NP428752.RAIg2QCCoOv5WPYzxxf-zTO7aSln3HJwRV3dFv0VDHZDI130_assertion dcterms:description "[Our present data based on selective interference with activation of endogenous Smad2 and Smad3 by stable expression of a mutant form of the TGF-beta type I receptor (RImL45) unable to bind Smad2/3 but with a functional kinase again show that reduction in Smad2/3 signaling by expression of RImL45 enhanced the malignancy of xenografted tumors of the well-differentiated MCF10A-derived tumor cell line MCF10CA1h, resulting in formation of larger tumors with a higher proliferative index and more malignant histologic features.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en; wi:evidence dgn-void:source_evidence_literature; sio:SIO_000772 miriam-pubmed:15231662; prov:wasDerivedFrom dgn-void:befree-20140225; prov:wasGeneratedBy eco:ECO_0000203 . dgn-void:befree-20140225 pav:importedOn "2014-02-25"^^xsd:date . dgn-void:source_evidence_literature a eco:ECO_0000212; rdfs:comment "Gene-disease associations inferred from text-mining the literature."@en; rdfs:label "DisGeNET evidence - LITERATURE"@en . } dgn-np:NP428752.RAIg2QCCoOv5WPYzxxf-zTO7aSln3HJwRV3dFv0VDHZDI130_publicationInfo { this: dcterms:created "2014-10-02T12:36:14+02:00"^^xsd:dateTime; dcterms:rights ; dcterms:rightsHolder dgn-void:IBIGroup; dcterms:subject sio:SIO_000983; prv:usedData dgn-void:disgenetrdf; pav:authoredBy , , , , ; pav:createdBy ; pav:version "v2.1.0.0" . dgn-void:disgenetrdf pav:version "v2.1.0" . }