@prefix this: <http://rdf.disgenet.org/resource/nanopub/NP1283919.RAIb2FFPN2KiE_ZoFR5CmeOdELEFZm8srmemWGpP495R4> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix sio: <http://semanticscience.org/resource/> .
@prefix ncit: <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#> .
@prefix lld: <http://linkedlifedata.com/resource/umls/id/> .
@prefix miriam-gene: <http://identifiers.org/ncbigene/> .
@prefix miriam-pubmed: <http://identifiers.org/pubmed/> .
@prefix eco: <http://purl.obolibrary.org/obo/> .
@prefix wi: <http://purl.org/ontology/wi/core#> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix pav: <http://purl.org/pav/> .
@prefix prv: <http://purl.org/net/provenance/ns#> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix dgn-np: <http://rdf.disgenet.org/resource/nanopub/> .
@prefix dgn-gda: <http://rdf.disgenet.org/resource/gda/> .
@prefix dgn-void: <http://rdf.disgenet.org/v4.0.0/void/> .

dgn-np:NP1283919.RAIb2FFPN2KiE_ZoFR5CmeOdELEFZm8srmemWGpP495R4130_head {
  this: np:hasAssertion dgn-np:NP1283919.RAIb2FFPN2KiE_ZoFR5CmeOdELEFZm8srmemWGpP495R4130_assertion;
    np:hasProvenance dgn-np:NP1283919.RAIb2FFPN2KiE_ZoFR5CmeOdELEFZm8srmemWGpP495R4130_provenance;
    np:hasPublicationInfo dgn-np:NP1283919.RAIb2FFPN2KiE_ZoFR5CmeOdELEFZm8srmemWGpP495R4130_publicationInfo;
    a np:Nanopublication .
  
  dgn-np:NP1283919.RAIb2FFPN2KiE_ZoFR5CmeOdELEFZm8srmemWGpP495R4130_assertion a np:Assertion .
  
  dgn-np:NP1283919.RAIb2FFPN2KiE_ZoFR5CmeOdELEFZm8srmemWGpP495R4130_provenance a np:Provenance .
  
  dgn-np:NP1283919.RAIb2FFPN2KiE_ZoFR5CmeOdELEFZm8srmemWGpP495R4130_publicationInfo
    a np:PublicationInfo .
}

dgn-np:NP1283919.RAIb2FFPN2KiE_ZoFR5CmeOdELEFZm8srmemWGpP495R4130_assertion {
  miriam-gene:6850 a ncit:C16612 .
  
  lld:C0023434 a ncit:C7057 .
  
  dgn-gda:DGN8a980d2f137098366904401f594b3f0d sio:SIO_000628 miriam-gene:6850, lld:C0023434;
    a sio:SIO_001121 .
}

dgn-np:NP1283919.RAIb2FFPN2KiE_ZoFR5CmeOdELEFZm8srmemWGpP495R4130_provenance {
  dgn-np:NP1283919.RAIb2FFPN2KiE_ZoFR5CmeOdELEFZm8srmemWGpP495R4130_assertion dcterms:description
      "[Our studies reveal that proximal kinases SYK and LYN are critical for the activation of mutant PLCG2 and that therapeutics targeting SYK and LYN can combat molecular resistance in cell line models and primary CLL cells from ibrutinib-resistant patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en;
    wi:evidence dgn-void:source_evidence_literature;
    sio:SIO_000772 miriam-pubmed:25972157;
    prov:wasDerivedFrom dgn-void:befree-2016;
    prov:wasGeneratedBy eco:ECO_0000203 .
  
  dgn-void:befree-2016 pav:importedOn "2016-02-19"^^xsd:date .
  
  dgn-void:source_evidence_literature a eco:ECO_0000212;
    rdfs:comment "Gene-disease associations inferred from text-mining the literature."@en;
    rdfs:label "DisGeNET evidence - LITERATURE"@en .
}

dgn-np:NP1283919.RAIb2FFPN2KiE_ZoFR5CmeOdELEFZm8srmemWGpP495R4130_publicationInfo {
  this: dcterms:created "2016-05-13T12:51:28+02:00"^^xsd:dateTime;
    dcterms:rights <http://opendatacommons.org/licenses/odbl/1.0/>;
    dcterms:rightsHolder dgn-void:IBIGroup;
    dcterms:subject sio:SIO_000983;
    prv:usedData dgn-void:disgenetv3.0rdf;
    pav:authoredBy <http://orcid.org/0000-0001-5999-6269>, <http://orcid.org/0000-0002-7534-7661>,
      <http://orcid.org/0000-0002-9383-528X>, <http://orcid.org/0000-0003-0169-8159>, <http://orcid.org/0000-0003-1244-7654>;
    pav:createdBy <http://orcid.org/0000-0003-0169-8159>;
    pav:version "v4.0.0.0" .
  
  dgn-void:disgenetv3.0rdf pav:version "v4.0.0" .
}