@prefix this: <http://www.tkuhn.ch/bel2nanopub/RAIUYzfnp33R3XFJ6EH4VxKBfyCne-3WxYohQMA56LLOU> .
@prefix sub: <http://www.tkuhn.ch/bel2nanopub/RAIUYzfnp33R3XFJ6EH4VxKBfyCne-3WxYohQMA56LLOU#> .
@prefix beldoc: <http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix dce: <http://purl.org/dc/elements/1.1/> .
@prefix pav: <http://purl.org/pav/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix belv: <http://www.selventa.com/vocabulary/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix sdis: <http://resource.belframework.org/belframework/20131211/namespace/selventa-legacy-diseases/> .
@prefix mgi: <http://www.informatics.jax.org/marker/MGI:> .
@prefix proteinModification: <http://www.ebi.ac.uk/ontology-lookup/?termId=MOD:00000> .
@prefix psimod: <http://www.ebi.ac.uk/ontology-lookup/?termId=MOD:> .
@prefix obo: <http://purl.obolibrary.org/obo/> .
@prefix occursIn: <http://purl.obolibrary.org/obo/BFO_0000066> .
@prefix species: <http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=> .
@prefix pubmed: <http://www.ncbi.nlm.nih.gov/pubmed/> .
@prefix orcid: <http://orcid.org/> .
sub:Head {
   this: np:hasAssertion sub:assertion ;
    np:hasProvenance sub:provenance ;
    np:hasPublicationInfo sub:pubinfo ;
    a np:Nanopublication .
}
sub:assertion {
   sub:_1 belv:variantOf mgi:2145955 ;
    a proteinModification: , psimod:00696 .
  sub:_2 occursIn: obo:CL_0000115 , species:10090 ;
    rdf:object sub:_1 ;
    rdf:predicate belv:increases ;
    rdf:subject sdis:response%20to%20shear%20stress ;
    a rdf:Statement .
  sub:assertion rdfs:label "path(SDIS:\"response to shear stress\") -> p(MGI:Prkaa1,pmod(P,T,183))" .
}
sub:provenance {
   beldoc: dce:description "Approximately 61,000 statements." ;
    dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ;
    dce:title "BEL Framework Large Corpus Document" ;
    pav:authoredBy sub:_4 ;
    pav:version "20131211" .
  sub:_3 prov:value "Shear stress, atorvastatin, and adiponectin all increased AMPK Thr172 (activating phosphorylation found at Thr183 on the Uniprot sequence Q5EG47) and eNOS Ser633 phosphorylations (Ser632 from sequence Uniprot P70313), which were abolished if AMPK was pharmacologically inhibited or genetically ablated. The constitutively active form of AMPK or an AMPK agonist caused a sustained Ser633 phosphorylation. " ;
    prov:wasQuotedFrom pubmed:19131647 .
  sub:_4 rdfs:label "Selventa" .
  sub:assertion prov:hadPrimarySource pubmed:19131647 ;
    prov:wasDerivedFrom beldoc: , sub:_3 .
}
sub:pubinfo {
   this: dct:created "2014-07-03T14:33:32.023+02:00"^^xsd:dateTime ;
    pav:createdBy orcid:0000-0001-6818-334X , orcid:0000-0002-1267-0234 .
}