sub:assertion {
d:DB00382 dv:ddi-interactor-in dr:DB00382_DB00850 .
d:DB00850 dv:ddi-interactor-in dr:DB00382_DB00850 .
dr:DB00382_DB00850 dct:identifier "drugbank_resource:DB00382_DB00850" ;
dct:title "DDI between Tacrine and Perphenazine - The therapeutic effects of the central acetylcholinesterase inhibitor (AChEI), Tacrine, and/or the anticholinergic/antipsychotic, Perphenazine, may be reduced due to antagonism. This interaction may be beneficial when the anticholinergic action is a side effect. AChEIs may also augment the central neurotoxic effect of antipsychotics. Monitor for extrapyramidal symptoms and decreased efficacy of both agents."@en ;
a dv:Drug-Drug-Interaction ;
rdfs:label "DDI between Tacrine and Perphenazine - The therapeutic effects of the central acetylcholinesterase inhibitor (AChEI), Tacrine, and/or the anticholinergic/antipsychotic, Perphenazine, may be reduced due to antagonism. This interaction may be beneficial when the anticholinergic action is a side effect. AChEIs may also augment the central neurotoxic effect of antipsychotics. Monitor for extrapyramidal symptoms and decreased efficacy of both agents. [drugbank_resource:DB00382_DB00850]"@en .
}