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kin(p(MGI:Chuk)) -> deg(p(MGI:Nfkbia))
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Approximately 61,000 statements.
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This finding agrees with previous studies that showed that IkBa is a better substrate for the IKKs than IkBb (17). The kinetics of IkBa and IkBb phosphorylation were coincident with the degradation of endogenous IkBa as well as the appearance of DNA-binding NF-kB complexes in the nucleus at approximately 15–30 min (Fig. 1B, bottom three panels).
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