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[From X-ray studies, it has been shown that the ligand-binding domains (LBD) of the two receptors are strikingly similar, and that only two changes fall within the binding cavity (ER alpha Leu384 to ER beta Met336, and ER alpha Met421 to ER beta Ile373).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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