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p(RGD:Npr2) -| p(RGD:Ngf)
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Approximately 61,000 statements.
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Copyright (c) 2011-2012, Selventa. All rights reserved.
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BEL Framework Large Corpus Document
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1.4
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When CNP(50 nM) was added to NGF(25 ng/ml)-treated cells, CNP was able to completely abolish the NGF-induced increase in proliferation. CNP also completely inhibited the increase in apoptosis of NST-positive cells in response to NGF. This suggests that in the absence of additional factors, many of the cells induced by NGF to proliferate undergo apoptosis, and that CNP was able to both inhibit this proliferation and save NGF-treated cells from subsequent apoptosis. Cnp signal through its receptor Npr2.
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Selventa
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2014-07-03T14:30:04.207+02:00
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