. . . . . . . . . . . . . . "a(CHEBI:ceramide) -> kin(p(SFAM:\"MAPK Erk1/2 Family\"))" . "Approximately 61,000 statements." . "Copyright (c) 2011-2012, Selventa. All rights reserved." . "BEL Framework Large Corpus Document" . . "20131211" . "We have previously shown that de novo-synthesized ceramide signals apoptosis in primary astrocytes via activation of the Raf-1/ERK cascade [8]. The e¡ect of AICAR on the activity of these two kinases was therefore determined. The palmitate- induced activation of ERK (Fig. 3A) and Raf-1 (Fig. 3B) was prevented by AICAR." . . "Selventa" . . . . "2014-07-03T14:31:39.568+02:00"^^ . . .