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kin(p(EGID:2475)) -> p(HGNC:MYC)
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Approximately 61,000 statements.
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Since both mTOR and PLD can stimulate Myc expression (107, 141), it is possible that the PLD-generated survival signals are mediated in part by stimulating Myc expression, which like PLD, can cooperate with signaling oncogenes to transform primary cells (71, 96, 124, 126). Estrogen also stimulates Myc expression in the estrogen receptor-positive MCF-7 breast cancer cell line (142), and the induction of Myc by estrogen has been proposed to contribute to the mitogenic effects of estrogen in breast epithelia and in breast cancer progression
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Selventa
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2014-07-03T14:30:17.051+02:00
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