NP638388.RAHWt3SYUM-bwdgzWinEViTrQtlmrLFHEixPdPIfZscBA
has assertion: NP638388.RAHWt3SYUM-bwdgzWinEViTrQtlmrLFHEixPdPIfZscBA130 assertion
has provenance: NP638388.RAHWt3SYUM-bwdgzWinEViTrQtlmrLFHEixPdPIfZscBA130 provenance
has publication info: NP638388.RAHWt3SYUM-bwdgzWinEViTrQtlmrLFHEixPdPIfZscBA130 publicationInfo
type: Nanopublication
created: 2016-05-13T12:46:34+02:00
rights: http://opendatacommons.org/licenses/odbl/1.0/
rights holder: IBIGroup
subject: SIO_000983
used data: disgenetv3.0rdf
authored by: http://orcid.org/0000-0001-5999-6269
authored by: http://orcid.org/0000-0002-7534-7661
authored by: 0000-0002-9383-528X
authored by: http://orcid.org/0000-0003-0169-8159
authored by: http://orcid.org/0000-0003-1244-7654
created by: http://orcid.org/0000-0003-0169-8159
version: v4.0.0.0

NP638388.RAHWt3SYUM-bwdgzWinEViTrQtlmrLFHEixPdPIfZscBA130 assertion
type: Assertion
description: [Finally, we tested the dual role of IL-1 in memory by intracerebroventricular (ICV) administration of different doses of IL-1beta and IL-1ra following learning, providing the first systematic evidence that the involvement of IL-1 in hippocampal-dependent memory follows an inverted U-shaped pattern, i.e., a slight increase in brain IL-1 levels can improve memory, whereas any deviation from the physiological range, either by excess elevation in IL-1 levels or by blockade of IL-1 signaling, results in impaired memory.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
evidence: DisGeNET evidence - LITERATURE
SIO_000772: http://identifiers.org/pubmed/17976923
was generated by: ECO_0000203

befree-2016
imported on: 2016-02-19

DisGeNET evidence - LITERATURE
type: ECO_0000212
comment: Gene-disease associations inferred from text-mining the literature.

disgenetv3.0rdf
version: v4.0.0