. . . . . . . . . . . . "bp(GOBP:\"response to hypoxia\") -> r(HGNC:LOX)" . "Approximately 61,000 statements." . "Copyright (c) 2011-2012, Selventa. All rights reserved." . "BEL Framework Large Corpus Document" . . "20131211" . "Human myofibroblasts turned to hypoxia-driven gene expression, indicated by VEGF expression, at oxygen concentrations of 4% and lower. Gene expression levels of procollagen alpha1(I) and alpha1(III) increased to 138??26% and 143??19% respectively, for all oxygen concentrations below 4%. At 2% O(2), LH2 and LOX gene expression levels were higher than control cultures (340??53% and 136??29% respectively) and these levels increased even further with decreasing oxygen concentrations (611??176% and 228??45% at 0.5% O(2) respectively). Elastin gene expression levels remained unaffected. Collagen synthesis and LH2 protein levels increased at oxygen concentrations of 2% and lower. Oxygen concentrations below 4% induce enhanced ECM production by human myofibroblasts." . . "Selventa" . . . . "2014-07-03T14:33:39.993+02:00"^^ . . .