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[Of immediate clinical importance is the fact that ?IKZF1 occurs in 15% of paediatric B-cell precursor acute lymphoblastic leukaemia (BCP ALL) and that the presence of ?IKZF1 is associated with an increased risk of relapse and a poor outcome; in some studies such deletions have been shown to be an independent risk factor also when minimal residual disease data are taken into account.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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